Solomon, Terry; Smith, Erin N.; Matsui, Hiroko; Brækkan, Sigrid Kufaas; Wilsgaard, Tom; Njølstad, Inger; Mathiesen, Ellisiv B.; Hansen, John-Bjarne; Frazer, Kelly A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-21)
Background—Genetic variation can be used to study causal relationships between biomarkers and diseases. Here, we
identify new common and rare genetic variants associated with cardiovascular-related protein levels (protein quantitative
trait loci [pQTLs]). We functionally annotate these pQTLs, predict and experimentally confirm a novel molecular
interaction, and determine which pQTLs are associated ...